Keyword
High altitude
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UV-B (wavelengths: 280-315 nm) solar radiation is measured by a silicon photodiode (Skye SKU 430).
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A Gas Chromatpgraph-FID (Agilent 6890N ) is used to measure methane (CH4), carbon monoxide (CO), nitrous oxide (N2O) and sulfur hexafluoride (SF6).
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The lungs play a pivotal role in adaptation to high altitude. The increase in ventilation and the rise in pulmonary artery pressure are the first features of lung response to hypoxic exposure. At high altitude the lungs can also be affected by high-altitude pulmonary oedema, a severe form of acute mountain sickness. In healthy subjects the ascent to high altitude is also associated with alterations in lung function, which have been in part interpreted as an effect of extra vascular lung fluid accumulation. The patterns of respiratory function changes at high altitude are discussed, taking into account the body fluid movement and the increase in endothelial permeability induced by hypoxic exposure. As the problem of “respiratory” patients at high altitude is very important, a short summary of the guidelines for altitude exposure of asthmatic and COPD patients is reported at the end of the chapter.
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A Gas Chromatpgraph-FID (Agilent 6890N ) is used to measure carbon monoxide (CO) strating from January 2008.
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A Gas Chromatpgraph-FID (Agilent 6890N ) is used to measure nitrous oxide.
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Visitors at high altitude are increasing in age and comorbidities, which can lead to a failure in acclimatization. We describe the development of acute mountain sickness (AMS) in a 44-year-old man with metabolic syndrome and the time- and altitude-dependent correlation between the development of AMS and blood pressure and heart rate changes. Our observations support a dominant role of endothelial dysfunction in the pathogenesis of AMS and suggest new behavioral indications