The Ev-K2-CNR Project has been promoting and developing research at high altitude (>2,500 m a.sl.) in the Himalaya and Karakoram since 1987. Recently, activities have been focused on development of a monitoring network (stations at High Altitude for Research on the Environment in Asia: SHARE-Asia) to increase the environmental and geophysical scientific knowledge in these mountain regions. Research and monitoring activity at high altitude require a particular experience and a well-organized network. Ev-K2-CNR has accumulated a significant experience in managing a high altitude network of automatic weather stations along the Khumbu Valley (Nepal) and in northern Pakistan (Baltistan region) in the framework of the Coordinated Enhanced Observing Period Project. With the installation of an Atmospheric Brown Clouds Project (ABC) monitoring station near the Pyramid Laboratory-Observatory in 2006, near the base of Mount Everest, SHARE-Asia can also contribute to the study of atmospheric circulation of pollutants. The “ABC-Pyramid” is the first of a network of stations that are planned to be installed at altitudes between 2,500 and 5,000 m a.s.l. along the Himalayan–Karakoram chain. These stations will be operated under active cooperation with the local scientific community, creating ample cooperation between western countries and developing countries in the region.