01bbfa99-0638-43e6-b895-c750825b2b79 eng Ev-K2-CNR +39 035 3230511 +39 035 3230551 Via San Bernardino 145 Bergamo BG 24126 Italy metadata@evk2cnr.org http://www.evk2cnr.org/ 2025-02-21T19:07:16 ISO 19115:2003/19139 1.0 WGS84 EPSG The hypoxic profile during trekking to the Pyramid Laboratory 2009-09-23T00:00:00 High Altitude Medicine & Biology (2009) Volume: 10 3 233-237 High Altitude Medicine & Biology (2009) Volume: 10, Issue: 3, 1527-0297 The oxygen saturation values reported in the high altitude literature are usually taken during a few minutes of measurement either at rest or during exercise. We aimed to investigate the daily hypoxic profile by monitoring oxygen saturation for 24h in 8 lowlanders (4 females, ages 26 to 59) during trekking from Lukla (2850m) to the Pyramid Laboratory (5050m). Oxygen saturation was measured (1) daily at each altitude (sm), (2) for 24-h during ascent to 3500m, 4200m, and on day 1 at 5050m (lm), and (3) during a standardized exercise (em). Results: (1) the sm and lm values were 90.9% (±0.5) and 86.4% (±1.1) at 3500m; 85.2%(±1.1), and 80% (±1.9) at 4200m; 83.8%(±1) and 77% (±1.7) at 5050m (p<0.05); (2) the daily time spent with oxygen saturation <90% was 56.5% at 3500m, 81% at 4200m, and 95.5% at 5050m; (3) during exercise, oxygen saturation decreased by 10.58%, 13.43%, and 11.24% at 3500, 4200, and 5050?m, respectively. In conclusion, our data show that the level of hypoxemia during trekking at altitude is more severe than expected on the basis of a short evaluation at rest and should be taken into account. Luciano Pomidori Department of Biomedical Sciences, University of Ferrara 3287858417 Corso Giovecca, 203 Ferrara FE 44100 Italy luca.pomidori@unife.it www.unife.it Daniela Rita Bonardi Institute of Diseases of the Respiratory System +39 0255033716 Via F.Sforza,35 Milano MI 20122 Italy Federica Campigotto Department of Cardio Thoracic and Vascular Desease, University of Milan Via F.Sforza,35 Milano MI 20122 Italy Valter Fasano Department of Cardio Thoracic and Vascular Desease, University of Milan +39 0255033716 Via F.Sforza,35 Milano MI 20122 Italy valter.fasano@unimi.it Alessandra Gennari National Institute for Cancer Research, Genoa Largo Rosanna Benzi,10 Genova Genova 16132 Italy alessandra.gennari@istge.it http://www.istge.it/ Gabriele Valli Clinical Medicine Department, Sapienza University of Rome v.le Università, 37 Roma ROMA 00185 Italy valli.gabriele@fastwebnet.it Paolo Palange Clinical Medicine Department, Sapienza University of Rome +39 0649972091 +39 064940421 v.le Università, 37 Roma ROMA 00185 Italy paolo.palange@uniroma1.it http://www.uniroma1.it/ Annalisa Cogo Biomedical Research Centre applied to sport, University of Ferrara +39 0532210420 +39 0532210297 Via Gramicia,35 Ferrara FE 44123 Italy annalisa.cogo@unife.it http://www.unife.it/centri/centro/studi-biomedici https://geoportal.mountaingenius.org/geonetwork/srv/api/records/01bbfa99-0638-43e6-b895-c750825b2b79/attachments/evk2cnr__.png evk2cnr__.png SHARE oxygen saturation trekking altitude hypoxemia Lukla the Pyramid Laboratory eng health 80.0522 88.1946 26.3684 30.4247 http://www.liebertonline.com/doi/abs/10.1089/ham.2008.1107 WWW:LINK-1.0-http--related The Hypoxic Profile during Trekking to the Pyramid Laboratory. Pomidori, L., D. Bonardi, F. Campigotto, V. Fasano, A. Gennari, G. Valli, P. Palange & A. Cogo. 2009. High Altitude Medicine & Biology, 10(3): 233-237.